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Wednesday, August 6, 2014

Radiology beyond X-Rays



The Era for radiology began in 1895, when a German physicist “Wilhelm Roentgen” made the discovery of X-Rays while experimenting with electron beams. Roentgen's remarkable discovery is one of the most important medical advancements in human history. X-ray technology lets physicians see straight through human tissue to examine bones and cavities with extraordinary ease. Roentgen received the first Nobel Prize in physics for their discovery in 1901. Plain radiography was the only imaging modality available during the first 50 years of radiology.

Over last 40 years significant advances have taken place in radiology creating a niche for itself and now an important part of new age medicine for both diagnosing and treating disease. 

A brief introduction to various imaging technology available: 

1.       Mammography:

It is an X-Ray based technology for examination of breast. Mammograms can be used as screening examination, aimed at detecting early breast cancer or better define clinically found abnormality like a lump in the breast. It should be only used after consultation with a doctor as it involves ionizing radiation. 

2.       Ultrasound: 

 "Ultrasound" refers to sound waves with a frequency too high for humans to hear. Ultrasound images (sonograms) are made by sending a pulse of ultrasound into tissue using an ultrasound  probe (transducer). The sound reflects and echoes off parts of the tissue; this echo is recorded and displayed as an image to the operator. Benefits of ultrasound are that it shows inside the human body in real time without any delay and is completely safe without any ionizing radiation. 

3.       CT Scan (computed tomography): 

CT scan is an X-Ray based technology, which uses computer-processed x-rays to see what is inside human body without cutting it. It produces virtual 'slices' of the area under scanning. It can also generate a 3D image. CT scanning has become the test of choice in diagnosing some urgent and emergent conditions, such as brain hemorrhage or acute abdominal pain, where the surgeon need to decide whether a surgery is required or not. In the past, the only option would be to reply on clinical signs and operate beyond a certain point. With CT scan advances, surgeon gets accurate diagnosis of the problem and location.  Based on the clinical information they, may operate only when required and at times even plan the surgery based on the images available and reducing surgical time.  CT scan uses ionizing radiation and should be used only after consulting your doctor.  

4.       MRI (Magnetic Resonance Imaging): 

An MRI machine uses magnetic field to create detailed images of the body. Human body contains water (hydrogen protons). MRI uses strong magnetic fields to align hydrogen protons within body tissues, and then uses a radio frequency pulse to disturb the axis of rotation of these nuclei and observes the signal generated as the nuclei return to their baseline states. MRI is non-ionizing and completely safe. An advantage of MRI is its ability to produce images in any plane of the body and gives the best soft tissue contrast of all the imaging modalities. Disadvantage includes tunnel like space leading to claustrophobia and noise during the exam.

5.       Nuclear medicine & PET (Positron Emission tomography)

Nuclear medicine imaging is a specialty in imaging, which involves administration radio-pharmaceuticals into the patient.  These radio-pharmaceuticals have affinity for certain body tissues and are labelled with radioactive tracer. The radiation, emitting from the body is detected by a gamma camera and an image is formed. 

PET CT is fusion of nuclear medicine images with a CT scan, both acquired simultaneously. The physiological information obtained from radiotracers is overlaid with the anatomical structures obtained via a CT scan. This improves diagnostic accuracy giving anatomical and functional information about tissues.
PET CT is one of the significant advances in cancer treatment. It has ionizing radiation and should be only performed under medical supervision and after consulting a doctor.

References: 

2.       http://www.sharecare.com

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